MANIFESTATION OF THE ORAL MUCOSA IN COVID-19

Abstract

The oral cavity is one of the main gates for coronavirus (SARS-CoV-2), the
oral cavity also suffers greatly from this infection in our body, because it is one of
the most vulnerable places. In addition, since the salivary glands can serve as a
reservoir of viruses and support their release into the external environment, it was
concluded that saliva, as a component of oral fluid, can play an important role in
the spread of coronavirus infection. This is mainly due to the ACE-2 receptor ,
which have a high level of expression in the keratinized surface of the epithelial
cells of the oral mucosa, especially in the epithelial cells of the dorsal part of the
tongue, tonsils, vocal cords, salivary glands and sinuses, due to which the virus
replicates in and causes both oral lesions and symptoms of sides of the mouth.
After entering the cell, the virus delays the immune system response, allowing the
infection to progress, and it becomes much more difficult to fight it. Accordingly,
due to the relatively high rate of COVID-19-associated complications, timely
diagnosis of clinical forms, including high-risk patients with prognosis their
clinical course and the selection of drug treatment appropriate to the severity of the
clinical course remain quite complex and debatable issues. It was emphasized that
in some cases, oral symptoms may be the initial or only sign of disease, and
dentists should therefore conduct a thorough clinical examination of the oral
cavity.