CONTEMPORARY CHARACTERISTICS OF ALPORT'S SYNDROME IN CHILDREN (literature review)

Abstract

. In order to study the modern characteristics of Alport syndrome in
children, the literature of the last decade was analyzed. It was found that in recent
years, the rate of Alport syndrome in children changes from year to year,
depending on the age of the mother, pathologies of the pregnancy period
(toxicosis, childbirth complications, kidney, cardiovascular and endocrine
diseases), marriage of close relatives, it became known that it is fundamentally
related to kidney diseases in children (glomerulopathies, pyelonephritis, metabolic
nephropathies) and immune deficiency. In the diagnosis of Alport syndrome,
dysembryogenetic stigmas (protruding eyebrow arch, eye and chest hypertelorism,
deep palate, defect of the auricle, sandal space between 1-2 fingers, clinodactyly,
syndactyly, kidneys congenital developmental defect) is important.