COMPARATIVE EVALUATION OF THE EFFECT OF EPLERENONE AND SPIRINOLACTONE ON LEFT VENTRICULAR SYSTOLIC FUNCTION IN PATIENTS WITH CHRONIC HEART FAILURE

Abstract

One of the most common clinical disorders that nevertheless has a
high rate of morbidity and death is heart failure (HF) [1]. As to the latest guidelines,
all patients with symptomatic heart failure who do not have any contraindications
to this therapy should have an MRA prescribed to them in order to lower their risk
of hospitalization and mortality from HF [2, 3].Objective. By measuring left
ventricle ejection fraction (LVEF) in patients with chronic heart failure, our study
aimed to compare the effectiveness of eplerenone vs. spironolactone on left
ventricular systolic function, particularly their effect on preventing hospitalization,
reducing mortality, and improving clinical status among patients with chronic HF